Open | 16 April – 16 May, 2024 |

An advanced school on physiology and pathophysiology of basal ganglia neuronal network. It provides cutting-edge insights concerning these structures, shedding light on their implication in the control of triggering and coordination of movement.

ABOUT THE SCHOOL

This is an advanced school on physiology and pathophysiology of basal ganglia neuronal network. It provides the latest insights concerning these structures and their implication in the control of triggering and coordination of movement. The program will also approach all pathologies induced by dysfunctioning of basal ganglia, particularly Parkinson’s disease, but also Hugtinton disease, Hemiballism, etc.

The program includes lectures on the most recent techniques used in this domain of research, such as deep brain stimulation and optogenetic. The school will commence with four days of technical workshop, during which students will learn how to stereotaxically inject 6-OHDA in the middle forebrain bundle to have an animal model of Parkinson’s Disease with dopaminergic depletion in the striatum. Then they will conduct behavioural and coordination tests to determine the impact of the 6-OHDA lesion on motor function. Following those tests, animals will be sacrificed and monoamines will be measured by high-phase liquid chromatography. A part of animals will be perfused with fixative solution to determine the content of tyrosine hydroxylase by immunohistochemistry. A second important technical workshop will utilize DREAD and chemogenetic to establish a correlation between Substancia Nigra and Nucleus Accumbens, a structure that can be involved in the addictive aspects of Parkinson’s disease.

Application period:
16 April – 16 May, 2024

School dates:
16-30 September, 2024

School location:
Faculty of Sciences, Ibn Battouta Avenue,
Rabat – Salé – Zemmour – Zaer, 1014
Morocco

Apply HERE

For any queries, please write to the organizer at nlakhdarghazal@gmail.com

Following the 4 days of hands-on workshop, lectures will start with basics on brain anatomy and neurochemistry, followed by specialized lectures on basal ganglia at anatomical and physiological level. Dysfunctioning of this neuronal network will be explained, as well as the diseases induced by this dysfunction. Many lectures will also address translational research aspects. The school program includes journal club sessions, student oral presentations, and roundtable networking. One full day will be spent at Hospital University Centre for Deep Brain Stimulation technique on Parkinsonian patients.

WHO CAN APPLY TO THIS SCHOOL?

  • Eligible applicants must be:
    • PhD students in their final years of thesis preparation,
    • post-doctoral fellows, or
    • early-career researchers, lecturers, neurologists, doctors, or psychiatrists
  • Only applicants residing in the Africa region are eligible to apply.

WHAT COSTS ARE COVERED FOR PARTICIPANTS?

  • Travel
  • Accommodation and meals
  • Local transportation

HOW TO APPLY?

Apply HERE by 16 May 2024.

Please note you will be redirected to the IBRO Grants Portal.