Axon guidance, the process that determines the direction and trajectory of growth of axons, is essential for the development of the nervous system. Studying the molecular and cellular mechanisms that control this process is important for understanding how the nervous system develops and for designing therapies for neural disorders.

Axon guidance is controlled by a variety of molecular and cellular mechanisms that act together to direct the growth of axons, including chemical, physical, and intrinsic guidance cues. One of the pioneers in the study of mechanisms of this process, Friedrich Bonhoeffer made fundamental contributions to the field. In the last Special Issue of Neuroscience, “Mechanisms of axon guidance: a tribute to pioneer Friedrich Bonhoeffer”, the scientific legacy of the neuroscientist is celebrated.

Read the Special Issue here.



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